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CD28 Monoclonal Antibody, FITC [NYRmCD28] (CPAB0363)

SKU:
CPAB0363
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
NYRmCD28
€660
Frequently bought together:

Description

system_update_alt Datasheet

CD28 Monoclonal Antibody, FITC [NYRmCD28] (CPAB0363)

The CD28 Antibody (FITC) (CPAB0363) is a specialized research tool designed for the study of CD28, an essential co-stimulatory molecule involved in T cell activation and immune response regulation. This polyclonal antibody, produced in rabbits, is highly specific to human samples and has been validated for use in flow cytometry applications. By binding specifically to the CD28 protein, this antibody allows for the detection and analysis of CD28 expression in various cell types, making it a valuable tool for immunology and cancer research studies.CD28 is a critical regulator of T cell activation, playing a key role in the immune response by providing the second signal necessary for T cell activation and proliferation.

Dysregulation of CD28 expression and signaling has been implicated in various diseases, including autoimmune disorders, infectious diseases, and cancer. Understanding the role of CD28 in immune response modulation is essential for developing therapeutic strategies that target T cell activation and control immune-mediated pathologies.The CD28 Antibody (FITC) (CPAB0363) offers researchers a reliable and specific tool for studying the function and expression of CD28 in various experimental settings. With its high reactivity and specificity for human samples, this antibody is an invaluable resource for investigating the role of CD28 in immune regulation and disease pathogenesis.

Product Name:CD28 Antibody, FITC
Product Sku:CPAB0363
Size:500μg
Host Species:Hamster
Immunogen:Purified mouse purified mouse LN T cells.
Clone:NYRmCD28.
Reactivity:Mouse
Applications:
Purification Method: Protein A
Isotype:IgG
Background:CD28 co-stimulation is necessary for CD4 positive T-cell proliferation & survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo. Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence.
Synonyms:
Storage Buffer:Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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