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CD28 Monoclonal Antibody [NYRmCD28] (CPAB0361)

SKU:
CPAB0361
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
NYRmCD28
€660
Frequently bought together:

Description

system_update_alt Datasheet

CD28 Monoclonal Antibody [NYRmCD28] (CPAB0361)

The CD28 Polyclonal Antibody (CPAB0361) is a vital tool for researchers studying the CD28 molecule, known for its role in T-cell activation and immune response regulation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the CD28 protein, this antibody enables precise detection and analysis in various cell types, making it an essential component for studies in immunology and cancer research.CD28 is a co-stimulatory receptor found on T-cells that plays a crucial role in the activation and proliferation of these immune cells.

Understanding the mechanisms by which CD28 functions is essential for unraveling the complexities of the immune response and for developing targeted therapies for diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. The CD28 Polyclonal Antibody provides researchers with a reliable tool for investigating the intricacies of CD28 biology and its role in immune system modulation.

Product Name:CD28 Antibody
Product Sku:CPAB0361
Size:500μg
Host Species:Hamster
Immunogen:Purified mouse purified mouse LN T cells.
Clone:NYRmCD28.
Reactivity:Mouse
Applications:
Purification Method: Protein A
Isotype:IgG
Background:CD28 co-stimulation is necessary for CD4 positive T-cell proliferation & survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo. Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence.
Synonyms:
Storage Buffer:Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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