CD28 Monoclonal Antibody, Biotin [NYRmCD28] (CPAB0362)
- SKU:
- CPAB0362
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Hamster
- Isotype:
- IgG
- Clone:
- NYRmCD28
Description
CD28 Monoclonal Antibody, Biotin [NYRmCD28] (CPAB0362)
The CD28 Antibody (Biotin) (CPAB0362) is a valuable tool for researchers studying CD28, a critical co-stimulatory molecule involved in T cell activation and regulation of immune responses. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically designed for use in Western blot applications.CD28 plays a pivotal role in the immune system by providing a secondary signal to T cells, enhancing their activation and promoting cytokine production. By targeting CD28 with this antibody, researchers can effectively detect and analyze the expression of CD28 in various cell types, facilitating studies in immunology, vaccine development, and autoimmune disease research.
Understanding the function of CD28 and its interaction with other immune molecules is essential for developing targeted therapies for conditions such as cancer, infectious diseases, and autoimmune disorders. The CD28 Antibody (Biotin) offers a reliable tool for investigating the role of CD28 in immune regulation and potential therapeutic interventions.
| Product Name: | CD28 Antibody, Biotin |
| Product Sku: | CPAB0362 |
| Size: | 500μg |
| Host Species: | Hamster |
| Immunogen: | Purified mouse purified mouse LN T cells. |
| Clone: | NYRmCD28. |
| Reactivity: | Mouse |
| Applications: |
| Purification Method: | Protein A |
| Isotype: | IgG |
| Background: | CD28 co-stimulation is necessary for CD4 positive T-cell proliferation & survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo. Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence. |
| Synonyms: | |
| Storage Buffer: | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
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