The CD275 Polyclonal Antibody (CAB23266) is a powerful tool for researchers studying CD275, a protein known for its role in immune regulation and immune response modulation. This polyclonal antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By specifically binding to the CD275 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in immunology and cancer research.CD275, also referred to as programmed death-ligand 1 (PD-L1), is a critical checkpoint molecule that plays a key role in immune evasion and tolerance. Its involvement in regulating T-cell responses and promoting immune tolerance has made CD275 a promising target for the development of immunotherapies in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function and regulation of CD275 is essential for designing effective treatments that modulate immune responses in these disease contexts.Overall, the CD275 Polyclonal Antibody (CAB23266) is a valuable tool for researchers investigating the role of CD275 in immune regulation and its potential as a therapeutic target in various disease settings. Its high reactivity, specificity, and validation for Western blot applications make it a reliable choice for research studies aiming to unravel the complexities of immune modulation and immune evasion mechanisms mediated by CD275.
Predicted to enable identical protein binding activity and signaling receptor binding activity. Involved in positive regulation of interleukin-4 production. Located in external side of plasma membrane. Is integral component of plasma membrane. Is expressed in several structures, including extraembryonic component; gonad; hemolymphoid system gland; liver; and stomach. Orthologous to human ICOSLG (inducible T cell costimulator ligand).
Purification Method:
Affinity purification
Gene ID:
50723
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse spleen, using CD275 Rabbit pAb (CAB23266) at 1:1500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
