CD27 Rabbit Monoclonal Antibody (CAB11505)
- SKU:
- CAB11505
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | CD27 Rabbit Monoclonal Antibody |
SKU: | CAB11505 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD27 (P26842). |
Sequence: | MARP HPWW LCVL GTLV GLSA TPAP KSCP ERHY WAQG KLCC QMCE PGTF LVKD CDQH RKAA QCDP CIPG VSFS PDHH TRPH CESC RHCN SGLL VRNC TITA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | T14; S152; Tp55; TNFRSF7; S152. LPFS2; CD27 |
Positive Sample: | THP-1,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 29kDa |
Observed MW: | 55kDa |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Purification Method: | Affinity purification |
Gene ID: | 939 |
Clone Number: | ARC0625 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |