CD27 Rabbit Polyclonal Antibody (CAB1945)
- SKU:
- CAB1945
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | CD27 Rabbit Polyclonal Antibody |
SKU: | CAB1945 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-191 of human CD27 (NP_001233.1). |
Sequence: | ATPA PKSC PERH YWAQ GKLC CQMC EPGT FLVK DCDQ HRKA AQCD PCIP GVSF SPDH HTRP HCES CRHC NSGL LVRN CTIT ANAE CACR NGWQ CRDK ECTE CDPL PNPS LTAR SSQA LSPH PQPT HLPY VSEM LEAR TAGH MQTL ADFR QLPA RTLS THWP PQRS LCSS DFIR |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | T14; S152; Tp55; TNFRSF7; S152. LPFS2; CD27 |
Positive Sample: | Raji,Mouse spleen,Mouse thymus,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 29kDa |
Observed MW: | 55kDa |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Purification Method: | Affinity purification |
Gene ID: | 939 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |