The Human CD27 Monoclonal Antibody (FITC Conjugated) (O323-AGEL1706) from AssayGenie is a powerful tool for researchers studying the CD27 protein, a key molecule involved in immune responses and signaling pathways. This antibody, specifically designed for use with human samples, is conjugated with FITC for easy detection and visualization in flow cytometry and immunofluorescence experiments.CD27, a member of the tumor necrosis factor receptor superfamily, plays a crucial role in the activation and differentiation of T and B cells, making it an important target in immunology research. By binding to the CD27 protein, this monoclonal antibody allows for precise detection and analysis of CD27 expression in various cell types, providing valuable insights into immune function and cell signaling mechanisms.
With its high specificity and sensitivity, the Human CD27 Monoclonal Antibody (FITC Conjugated) is a valuable tool for investigating the role of CD27 in immune responses, autoimmune diseases, and cancer biology. Researchers can leverage this antibody to further understand the functions and interactions of CD27, paving the way for the development of novel therapeutic strategies targeting this critical immune regulator.Enhance your research with the Human CD27 Monoclonal Antibody (FITC Conjugated) from AssayGenie and unlock new possibilities in immunology, oncology, and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P26842
Gene ID:
939
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.