The CD248 Polyclonal Antibody (CAB12706) is a valuable tool for researchers studying CD248, a transmembrane glycoprotein involved in angiogenesis and inflammation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CD248 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it well-suited for studies in immunology and cancer research.CD248, also known as endosialin, is an important regulator of vascular development and fibrosis, with implications in tumor growth and metastasis.
Its role in promoting angiogenesis and modulating inflammatory responses positions CD248 as a promising target for therapeutic interventions in conditions such as cancer, fibrosis, and cardiovascular diseases. Understanding the function of CD248 is essential for designing targeted therapies that can effectively modulate these biological processes.
Product Name:
CD248 Rabbit Polyclonal Antibody
SKU:
CAB12706
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-150 of human CD248 (NP_065137.1).
Predicted to enable extracellular matrix binding activity and extracellular matrix protein binding activity. Predicted to be involved in cell migration. Predicted to act upstream of or within several processes, including anatomical structure regression; lymph node development; and positive regulation of endothelial cell apoptotic process. Located in extracellular exosome.
Purification Method:
Affinity purification
Gene ID:
57124
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using CD248 Rabbit pAb (CAB12706) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
