The CD248 Polyclonal Antibody (CAB12703) is a specialized research tool for studying CD248, a cell surface protein associated with angiogenesis and fibroblast activation. This antibody, produced in rabbits, is highly specific to human CD248 and has been validated for Western blot applications. By binding to the CD248 protein, this antibody enables precise detection and analysis of CD248 expression in various cell types, making it essential for research in vascular biology, tumor microenvironment, and fibrosis.CD248, also known as endosialin, is a key player in promoting angiogenesis and fibroblast activation, processes involved in tissue remodeling and wound healing.
Dysregulation of CD248 has been implicated in diseases such as cancer, fibrosis, and inflammatory disorders. Therefore, studying the role of CD248 can provide insights into disease mechanisms and potential therapeutic targets aimed at disrupting abnormal angiogenesis or fibrosis.Overall, the CD248 Polyclonal Antibody is a powerful tool for researchers investigating the functions of CD248 in various physiological and pathological conditions, and it holds great promise for advancing our understanding of angiogenesis, fibroblast biology, and disease mechanisms.
Product Name:
CD248 Rabbit Polyclonal Antibody
SKU:
CAB12703
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-150 of human CD248 (NP_065137.1).
Predicted to enable extracellular matrix binding activity and extracellular matrix protein binding activity. Predicted to be involved in cell migration. Predicted to act upstream of or within several processes, including anatomical structure regression; lymph node development; and positive regulation of endothelial cell apoptotic process. Located in extracellular exosome.
Purification Method:
Affinity purification
Gene ID:
57124
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD248 Rabbit pAb (CAB12703) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
