The CD23 Rabbit Monoclonal Antibody is a powerful tool for researchers studying CD23, a cell surface protein involved in immune regulation and allergic responses. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for various research applications, including Western blot analysis.CD23, also known as Fc epsilon RII, is a key player in the immune response, particularly in controlling the production of immunoglobulin E (IgE) and modulating allergic reactions. Its role in regulating the immune system's response to antigens and pathogens makes it a promising target for investigating diseases like allergies, asthma, and autoimmune disorders.
By targeting CD23, researchers can gain valuable insights into the underlying mechanisms of these conditions and potentially develop new therapeutic strategies.Overall, the CD23 Rabbit Monoclonal Antibody is a valuable tool for scientists interested in unraveling the complexities of the immune system and exploring potential targets for novel treatments in immunology and allergy research.
Product Name:
CD23 Rabbit Monoclonal Antibody
SKU:
CAB11436
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 222-321 of human CD23 (P06734).
Cell membrane, Lipid-anchor, Secreted, Single-pass type II membrane protein.
Calculated MW:
36kDa
Observed MW:
45kDa
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
2208
Clone Number:
ARC0596
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Raji cells, using CD23 Rabbit mAb (CAB11436) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
