null

CD21 Monoclonal Antibody, Biotin [hCD21] (CPAB0319)

SKU:
CPAB0319
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
hCD21
€660
Frequently bought together:

Description

system_update_alt Datasheet

CD21 Monoclonal Antibody, Biotin [hCD21] (CPAB0319)

The CD21 Polyclonal Antibody (CPAB0319) is a crucial tool for researchers studying CD21, a cell surface protein involved in immune regulation and response. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By specifically binding to the CD21 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential resource for studies in immunology and cancer research.

CD21, also known as complement receptor 2, plays a key role in immune function by aiding in the activation of B cells and enhancing the immune response. Its involvement in these processes makes it a promising target for research in autoimmune disorders, infectious diseases, and cancer. By studying the function and expression of CD21, researchers can gain insights that may lead to the development of new therapeutic strategies aimed at modulating immune responses and treating various disorders.

Product Name:CD21 Antibody, Biotin
Product Sku:CPAB0319
Size:500μg
Host Species:Mouse
Immunogen:Purified human B-Cells.
Clone:hCD21.
Reactivity:Human
Applications:
Purification Method: Protein A
Isotype:IgG2a
Background:CD21 is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
Synonyms:Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CD21 antigen, CR2, C3DR, CD21, SLEB9.
Storage Buffer:Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Related Products