The CD200R1 Polyclonal Antibody is a valuable tool for researchers studying the CD200R1 cell surface molecule, known for its role in immune regulation and the inhibition of immune responses. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications. It specifically binds to the CD200R1 protein, allowing for easy detection and analysis in various cell types, making it ideal for studies in immunology and cancer research.CD200R1, also known as immune inhibitory receptor, is crucial for maintaining immune homeostasis by regulating inflammation and inhibiting allergic reactions.
Its importance in immune response modulation makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD200R1 is essential for the development of therapies that can manipulate immune function in these disease contexts.Overall, the CD200R1 Polyclonal Antibody offers researchers a reliable tool for investigating the role of CD200R1 in immune regulation and immune-related diseases, providing valuable insights for the development of novel therapeutic strategies.
Product Name:
CD200R1 Polyclonal Antibody
SKU:
CAB24670
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-240 of human CD200R1 (NP_740750.1).
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
OX2R; MOX2R; CD200R; HCRTR2; CD200R1
Positive Sample:
Daudi,A-431
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Secreted, Single-pass type I membrane protein, Single-pass type I membrane protein.
Calculated MW:
37kDa
Observed MW:
37kDa
This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
131450
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CD200R1 Rabbit pAb (CAB24670) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
