CD1D Rabbit Polyclonal Antibody (CAB1760)
- SKU:
- CAB1760
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | CD1D Rabbit Polyclonal Antibody |
SKU: | CAB1760 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human CD1D (NP_001757.1). |
Sequence: | EVPQ RLFP LRCL QISS FANS SWTR TDGL AWLG ELQT HSWS NDSD TVRS LKPW SQGT FSDQ QWET LQHI FRVY RSSF TRDV KEFA KMLR LSYP LELQ VSAG CEVH PGNA SNNF FHVA FQGK DILS FQGT SWEP TQEA PLWV NLAI QVLN QDKW TRET VQWL LNGT CPQF VSG |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | R3; CD1A; R3G1; CD1D |
Positive Sample: | THP-1,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein. |
Calculated MW: | 38kDa |
Observed MW: | 38kDa/50kDa |
This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 912 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |