CD1B Rabbit Polyclonal Antibody (CAB6551)
- SKU:
- CAB6551
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | CD1B Rabbit Polyclonal Antibody |
SKU: | CAB6551 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-303 of human CD1B (NP_001755.1). |
Sequence: | SEHA FQGP TSFH VIQT SSFT NSTW AQTQ GSGW LDDL QIHG WDSD SGTA IFLK PWSK GNFS DKEV AELE EIFR VYIF GFAR EVQD FAGD FQMK YPFE IQGI AGCE LHSG GAIV SFLR GALG GLDF LSVK NASC VPSP EGGS RAQK FCAL IIQY QGIM ETVR ILLY ETCP RYLL GVLN AGKA DLQR QVKP EAWL SSGP SPGP GRLQ LVCH VSGF YPKP VWVM WMRG EQEQ QGTQ LGDI LPNA NWTW YLRA TLDV ADGE AAGL SCRV KHSS LEGQ DIIL YWRN PTSI GS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | R1; CD1; CD1A; CD1B |
Positive Sample: | NCI-H125 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein. |
Calculated MW: | 37kDa |
Observed MW: | 47kDa |
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
Purification Method: | Affinity purification |
Gene ID: | 910 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |