The CD18 Rabbit Monoclonal Antibody (CAB19012) is a high-quality research tool specifically designed for the detection and analysis of CD18, a key cell surface molecule involved in immune responses and cell adhesion. This antibody, developed through the use of rabbit monoclonal technology, is highly reactive with human samples and has been validated for use in various applications, including Western blotting.CD18, also known as integrin beta-2, plays a crucial role in mediating cell-cell interactions and is integral to processes such as leukocyte migration and immune response regulation.
By targeting the CD18 protein, researchers can gain valuable insights into the mechanisms underlying immune function, inflammation, and various disease states.This antibody is ideal for studies in immunology, cancer research, and other fields where understanding cell adhesion and immune responses is essential. Its specificity and reliability make it a valuable tool for researchers looking to delve deeper into the role of CD18 in health and disease, paving the way for potential therapeutic interventions and targeted treatments in the future.
Product Name:
CD18 Rabbit Monoclonal Antibody
SKU:
CAB19012
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CD18 (P05107).
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3689
Clone Number:
ARC0400
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of U-937 cells, using CD18 antibody (CAB19012) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
