CD177 Rabbit Polyclonal Antibody (CAB6550)
- SKU:
- CAB6550
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CD177 Rabbit Polyclonal Antibody |
SKU: | CAB6550 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-285 of human CD177 (NP_065139.2). |
Sequence: | VSDL PRQW TPKN TSCD SGLG CQDT LMLI ESGP QVSL VLSK GCTE AKDQ EPRV TEHR MGPG LSLI SYTF VCRQ EDFC NNLV NSLP LWAP QPPA DPGS LRCP VCLS MEGC LEGT TEEI CPKG TTHC YDGL LRLR GGGI FSNL RVQG CMPQ PVCN LLNG TQEI GPVG MTEN CDMK DFLT CHRG TTIM THGN LAQE PTDW TTSN TEMC EVGQ VCQE TLLL LDVG LTST LVGT KGCS TVGA QNSQ KTTI HSAP PGV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP; CD177 |
Positive Sample: | BT-474,Mouse liver,Mouse bone marrow |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor. |
Calculated MW: | 51kDa |
Observed MW: | 105kDa/45kDa |
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
Purification Method: | Affinity purification |
Gene ID: | 57126 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |