The CD166 Antigen Polyclonal Antibody (CAB2218) is a valuable tool for research involving CD166, a cell surface antigen associated with various functions including cell adhesion, migration, and signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.CD166, also known as activated leukocyte cell adhesion molecule (ALCAM), is known to play a critical role in diverse biological processes such as immune response, neural development, and cancer metastasis. By specifically binding to the CD166 antigen, this antibody enables precise detection and analysis of CD166 expression in different cell types, making it an essential tool for studies in immunology, neuroscience, and oncology research.
The CD166 Antigen Polyclonal Antibody is particularly valuable for investigating the role of CD166 in various physiological and pathological processes, including immune cell interactions, neuronal development, and tumor progression. By gaining insights into the molecular mechanisms involving CD166, researchers can potentially develop novel therapeutic strategies for diseases such as cancer, neurodegenerative disorders, and autoimmune conditions.
Product Name:
CD166/ALCAM Rabbit Polyclonal Antibody
SKU:
CAB2218
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-180 of human CD166/CD166/ALCAM (NP_001618.2).
Membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
65kDa
Observed MW:
105kDa
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Purification Method:
Affinity purification
Gene ID:
214
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD166/ALCAM Rabbit pAb (CAB2218) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
