CD163 Polyclonal Antibody (CAB23023)
- SKU:
- CAB23023
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- IF
Frequently bought together:
Description
Product Name: | CD163 Polyclonal Antibody |
SKU: | CAB23023 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 42-261 of human CD163 (NP_004235.4?). |
Sequence: | SSLG GTDK ELRL VDGE NKCS GRVE VKVQ EEWG TVCN NGWS MEAV SVIC NQLG CPTA IKAP GWAN SSAG SGRI WMDH VSCR GNES ALWD CKHD GWGK HSNC THQQ DAGV TCSD GSNL EMRL TRGG NMCS GRIE IKFQ GRWG TVCD DNFN IDHA SVIC RQLE CGSA VSFS GSSN FGEG SGPI WFDD LICN GNES ALWN CKHQ GWGK HNCD HAED AGVI CSKG |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | M130; MM130; SCARI1; CD163 |
Positive Sample: | 293T transfected with CD63 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 125kDa |
Observed MW: | 160kDa |
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9332 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |