CD163 Monoclonal Antibody (CAB22619)
- SKU:
- CAB22619
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IF
Frequently bought together:
Description
Product Name: | CD163 Monoclonal Antibody |
SKU: | CAB22619 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 861-961 of human CD163 (NP_004235.4). |
Sequence: | GVVC RQLG CADK GKIN PASL DKAM SIPM WVDN VQCP KGPD TLWQ CPSS PWEK RLAS PSEE TWIT CDNK IRLQ EGPT SCSG RVEI WHGG SWGT VCDD SWDL D |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:200 |
Synonyms: | M130; MM130; SCARI1; CD163 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted |
Calculated MW: | 125kDa |
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9332 |
Clone Number: | ARC58325 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |