The CD155 Polyclonal Antibody is a valuable tool for researchers studying CD155, a cell surface molecule involved in immune responses and cancer progression. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds to the CD155 protein, allowing for detection and analysis in a variety of cell types, making it an ideal choice for studies in immunology and oncology research.CD155, also known as the poliovirus receptor (PVR), is a key player in immune regulation and has been implicated in the development and progression of various types of cancer.
Understanding the role of CD155 in immune responses and tumor growth is essential for developing targeted therapies and immunotherapies that aim to modulate immune function and treat cancer effectively. The CD155 Polyclonal Antibody provides researchers with a reliable tool to investigate the function of CD155 and its potential as a therapeutic target in cancer and immune-related diseases.
Product Name:
CD155 Polyclonal Antibody
SKU:
CAB24851
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-343 of human CD155 (NP_006496.4).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
39kDa/40kDa/42kDa/45kDa
Observed MW:
70kDa
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5817
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD155 Rabbit pAb (CAB24851) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC): Daudi.Exposure time: 30s.
