The CD151 Antigen Polyclonal Antibody (CAB1930) is a valuable tool for research involving the CD151 antigen, a cell surface protein that plays a crucial role in cell adhesion and migration. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CD151 antigen, researchers can detect and analyze its presence in various cell types, making it an essential tool for studies in cell biology, cancer research, and developmental biology.
CD151, a member of the tetraspanin family, is known for its involvement in the regulation of cell motility, invasion, and metastasis. Its role in facilitating cell-to-cell interactions and signal transduction pathways makes it a key target for understanding processes such as angiogenesis, wound healing, and tumor progression. Research into the function of CD151 is vital for uncovering potential therapeutic targets for cancer treatment and other diseases where cell adhesion and migration are dysregulated.
Product Name:
CD151 Rabbit Polyclonal Antibody
SKU:
CAB1930
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 113-221 of human CD151 (NP_004348.2).
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
977
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat uterus, using CD151 Rabbit pAb (CAB1930) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
