The CD14 Rabbit Monoclonal Antibody (CAB19011) is a powerful tool for researchers studying CD14, a key cell surface receptor involved in immune response regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications.CD14 plays a crucial role in the activation of immune responses and the detection of pathogens in the body. By targeting the CD14 protein, this antibody enables accurate detection and analysis in various cell types, making it an invaluable asset for studies in immunology, infectious diseases, and inflammation.
With its ability to target CD14, researchers can gain insights into the mechanisms of immune response activation and regulation, offering potential applications in the development of therapies for conditions such as sepsis, inflammatory disorders, and infectious diseases. The CD14 Rabbit Monoclonal Antibody (CAB19011) is a reliable tool for advancing research in these important areas of biomedical science.
Product Name:
CD14 Rabbit Monoclonal Antibody
SKU:
CAB19011
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CD14 (P08571).
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein.
Purification Method:
Affinity purification
Gene ID:
929
Clone Number:
ARC0353
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD14 Rabbit mAb (CAB19011) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.