CD138/Syndecan-1 Monoclonal Antibody (CAB23248)
- SKU:
- CAB23248
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
Description
| Product Name: | CD138/Syndecan-1 Monoclonal Antibody |
| SKU: | CAB23248 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human |
| Immunogen: | Recombinant protein of human CD138/Syndecan-1. |
| Tested Applications: | IHC-P ELISA |
| Recommended Dilution: | IHC-P,1:50 - 1:200 |
| Synonyms: | SDC; CD138; SYND1; syndecan; CD138/Syndecan-1 |
| Conjugate: | Unconjugated |
| Cellular Localization: | Membrane, Secreted, Single-pass type I membrane protein. |
| Calculated MW: | 32kDa |
| Observed MW: | Refer to figures |
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
| Purification Method: | Affinity purification |
| Gene ID: | 6382 |
| Clone Number: | ARC60158 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
 | Immunohistochemistry analysis of paraffin-embedded human appendix using CD138/Syndecan-1 Rabbit mAb (CAB23248) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. |
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