The CD132 IL-2R Gamma Monoclonal Antibody is a specialized tool for researchers studying the IL-2 receptor gamma chain, an essential component of the IL-2 receptor complex. This monoclonal antibody, produced using cutting-edge technology, specifically recognizes and binds to the CD132 protein, allowing for precise detection and analysis in experimental settings.The IL-2 receptor gamma chain is involved in cytokine signaling and is crucial for the proper functioning of the immune system. Dysregulation of this protein has been linked to various immune-related disorders, making it a key target for investigation in the fields of immunology and oncology.
This monoclonal antibody is highly specific for human samples and is validated for use in a variety of applications, including Western blotting, immunoprecipitation, and flow cytometry. Its reliability and accuracy make it an indispensable tool for researchers seeking to deepen their understanding of immune responses and potentially identify new therapeutic targets for diseases such as cancer and autoimmune disorders.
Product Name:
CD132/IL-2 R gamma Monoclonal Antibody
SKU:
CAB22037
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CD132/IL-2 R gamma (NP_000197.1).
P64; CIDX; IMD4; CD132; SCIDX; IL-2RG; SCIDX1; CD132/IL-2 R gamma
Positive Sample:
Jurkat,Mouse spleen,Mouse thymus
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Cell surface
Calculated MW:
42kDa
Observed MW:
50-70kDa
The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
Purification Method:
Affinity purification
Gene ID:
3561
Clone Number:
ARC54566
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD132/IL-2 R gamma antibody (CAB22037) at1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
