CD123 Polyclonal Antibody (CAB22111)
- SKU:
- CAB22111
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | CD123 Polyclonal Antibody |
SKU: | CAB22111 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-305 of human CD123 (NP_002174.1). |
Sequence: | KEDP NPPI TNLR MKAK AQQL TWDL NRNV TDIE CVKD ADYS MPAV NNSY CQFG AISL CEVT NYTV RVAN PPFS TWIL FPEN SGKP WAGA ENLT CWIH DVDF LSCS WAVG PGAP ADVQ YDLY LNVA NRRQ QYEC LHYK TDAQ GTRI GCRF DDIS RLSS GSQS SHIL VRGR SAAF GIPC TDKF VVFS QIEI LTPP NMTA KCNK THSF MHWK MRSH FNRK FRYE LQIQ KRMQ PVIT EQVR DRTS FQLL NPGT YTVQ IRAR ERVY EFLS AWST PQRF ECDQ EEGA NTRA WR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra; IL-3R-alpha |
Positive Sample: | Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | external side of plasma membrane, plasma membrane |
Calculated MW: | 43kDa |
Observed MW: | 70kDa |
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.
Purification Method: | Affinity purification |
Gene ID: | 3563 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |