The CD11b ITAM Rabbit Monoclonal Antibody (CAB19010) is a cutting-edge tool for researchers studying CD11b, a cell surface receptor involved in immune response and cellular adhesion processes. This high-quality antibody, generated in rabbits, exhibits exceptional reactivity with human samples and has been extensively validated for use in Western blot applications.CD11b, also known as integrin alpha M, is a key player in the regulation of immune responses and is implicated in various inflammatory conditions and diseases such as cancer. By specifically binding to the CD11b protein, this monoclonal antibody enables accurate detection and analysis of CD11b expression in a variety of cell types.
Its versatility and reliability make it an ideal choice for investigations in immunology, cancer biology, and other fields where CD11b is a focus of interest.Uncover the intricate functions of CD11b and its role in immune modulation with the CD11b ITAM Rabbit Monoclonal Antibody (CAB19010). This powerful tool provides researchers with the means to unlock new insights into the complex mechanisms underlying immune responses and disease pathogenesis.
Product Name:
CD11b/ITGAM Rabbit Monoclonal Antibody
SKU:
CAB19010
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1053-1152 of human CD11b/ITGAM (P11215).
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3684
Clone Number:
ARC0414
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using CD11b/ITGAM Rabbit mAb (CAB19010) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
