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CD11b Monoclonal Antibody, Biotin [hCD11b] (CPAB0328)

SKU:
CPAB0328
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
hCD11b
€660
Frequently bought together:

Description

system_update_alt Datasheet

CD11b Monoclonal Antibody, Biotin [hCD11b] (CPAB0328)

The CD11b Antibody (Biotin) - CPAB0328 is a high-quality research tool designed for studies involving CD11b, a cell surface molecule primarily expressed on macrophages, monocytes, and granulocytes. This antibody, produced in rabbits, is specifically reactive with human CD11b and is validated for use in various applications such as flow cytometry and immunohistochemistry.CD11b, also known as integrin alpha M, plays a crucial role in immune response regulation and cell adhesion processes. It is involved in cell migration, phagocytosis, and immune cell activation, making it a key player in inflammatory responses and host defense mechanisms. The CD11b Antibody (Biotin) - CPAB0328 enables detection and analysis of CD11b expression in different cell types, allowing researchers to investigate its role in immunology, inflammation, and various disease states.

By understanding the function of CD11b and its interactions with other molecules, researchers can gain valuable insights into inflammatory diseases, autoimmune disorders, and cancer progression. The CD11b Antibody (Biotin) - CPAB0328 is a valuable tool for studying the biology of CD11b and its implications in various pathological conditions, paving the way for potential therapeutic interventions targeting this important immune regulator.

Product Name:CD11b Antibody, Biotin
Product Sku:CPAB0328
Size:500μg
Host Species:Mouse
Immunogen:Purified human PBL Monocytes.
Clone:hCD11b.
Reactivity:Human
Applications:
Purification Method:Ion exchange column.
Isotype:IgG1
Background:Integrins are heterodimeric integral membrane proteins consisting of an ? chain and a ? chain. CD11b is an I-domain including ? integrin combines with the ? 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor also called MAC1. The M beta 2 integrin is crucial in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms:Integrin alpha-M, Cell surface glycoprotein MAC-1 subunit alpha, CR-3 alpha chain, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b antigen, ITGAM, CR3A, MO1A, CD11B, MAC-1, MAC1A, MGC117044.
Storage Buffer:Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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