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CD11a Monoclonal Antibody [mCD11a] (CPAB0353)

SKU:
CPAB0353
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
mCD11a
€660
Frequently bought together:

Description

system_update_alt Datasheet

CD11a Monoclonal Antibody [mCD11a] (CPAB0353)

The CD11a Polyclonal Antibody (CPAB0353) is a valuable tool for researchers studying CD11a, a cell surface adhesion molecule involved in immune responses. This antibody, produced in rabbits, is highly specific and reacts with human samples, making it suitable for use in Western blot assays. By binding to the CD11a protein, this antibody allows for the detection and analysis of CD11a in various cell types, facilitating research in immunology and cancer biology.CD11a, also known as integrin alpha L, plays a crucial role in immune cell adhesion and migration, contributing to the regulation of inflammatory responses and immune cell activation.

Research into CD11a function is essential for understanding immune system function and developing potential therapies for diseases such as cancer and autoimmune disorders. The CD11a Polyclonal Antibody provides researchers with a reliable tool for investigating the role of CD11a in health and disease.

Product Name:CD11a Antibody
Product Sku:CPAB0353
Size:500μg
Host Species:Rat
Immunogen:Enriched mouse peritoneal macrophages.
Clone:mCD11a.
Reactivity:Mouse
Applications:
Purification Method:Ion exchange column.
Isotype:IgG2b
Background:ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling.
Synonyms:Integrin, alpha L, CD11A, p180, alpha polypeptide, ITGAL, LFA-1, LFA1A TypeRat Anti Mouse Monoclonal.
Storage Buffer:Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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