The CD117 (c-Kit) Monoclonal Antibody (CAB23299) is a valuable tool for researchers studying the CD117 protein, also known as c-Kit, which plays a critical role in cell signaling and differentiation. This monoclonal antibody, produced in mouse, is highly specific for human samples and has been validated for use in various applications, including Western blot, immunohistochemistry, and flow cytometry.CD117 (c-Kit) is a receptor tyrosine kinase that is essential for the development and function of a variety of cell types, including hematopoietic stem cells, mast cells, and melanocytes. Dysregulation of the CD117 signaling pathway has been implicated in various diseases, including cancer and certain hematologic disorders.
Therefore, the CD117 (c-Kit) Monoclonal Antibody is a valuable tool for researchers investigating the role of CD117 in both normal physiology and disease pathology.With its high specificity and versatility in various research applications, the CD117 (c-Kit) Monoclonal Antibody (CAB23299) is an essential reagent for studies in cell biology, immunology, and cancer research. Researchers can rely on this antibody to accurately detect and analyze the expression of CD117 (c-Kit) in different cell types and tissues, aiding in the advancement of scientific knowledge and the development of potential therapeutic strategies targeting CD117 signaling pathways.
The c-Kit proto-oncogene is the cellular homolog of the transforming gene of a feline retrovirus (v-Kit). The c-kit protein includes characteristics of a protein kinase transmembrane receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
16590
Clone Number:
ARC60558
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts from mouse lung, using CD117/c-Kit Rabbit mAb (CAB23299) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
