The CD112 Polyclonal Antibody is a valuable tool for researchers studying the CD112 protein, a cell surface molecule with important implications in immune regulation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CD112 protein, this antibody allows for accurate detection and analysis in various cell types, making it an ideal choice for studies in immunology and cancer research.
CD112, also known as nectin-2, is involved in modulating immune responses by interacting with receptors on other cells. Research on CD112 is crucial for understanding how the immune system functions and how it can be manipulated in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By studying CD112, researchers can gain insights into potential therapeutic strategies for immune-related diseases.
Product Name:
CD112 Polyclonal Antibody
SKU:
CAB23657
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant protein of mouse CD112.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:1000 - 1:5000
Synonyms:
MPH; Pvr; Pvs; Cd112; Pvrl2; nectin-2; CD112
Positive Sample:
Molt-4,C2C12
Conjugate:
Unconjugated
Calculated MW:
57kDa
Observed MW:
65-85kDa
Enables cell adhesion molecule binding activity and protein homodimerization activity. Involved in homophilic cell adhesion via plasma membrane adhesion molecules. Acts upstream of or within several processes, including establishment of mitochondrion localization; sperm mitochondrion organization; and spermatid development. Located in cell-cell contact zone; plasma membrane; and zonula adherens. Is expressed in brain; cochlea; enamel organ; male reproductive system; and primitive collecting duct. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple sclerosis. Orthologous to human NECTIN2 (nectin cell adhesion molecule 2).
Purification Method:
Affinity purification
Gene ID:
19294
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CD112 Rabbit pAb (CAB23657) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
