CD105 Rabbit Monoclonal Antibody (CAB19008)
- SKU:
- CAB19008
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | CD105 Rabbit Monoclonal Antibody |
SKU: | CAB19008 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CD105/Endoglin (P17813). |
Sequence: | MDRG TLPL AVAL LLAS CSLS PTSL AETV HCDL QPVG PERG EVTY TTSQ VSKG CVAQ APNA ILEV HVLF LEFP TGPS QLEL TLQA SKQN GTWP REVL LVLS VNSS VFLH LQAL GIPL HLAY NSSL VTFQ EPPG VNTT ELPS FPKT QILE WAAE RGPI TSAA ELND PQSI LLRL GQAQ GSLS FCML EASQ DMGR TLEW RPRT |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | END; HHT1; ORW1; CD105/Endoglin |
Positive Sample: | HUVEC |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 71kDa |
Observed MW: | 90kDa |
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2022 |
Clone Number: | ARC0446 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |