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CD105 Polyclonal Antibody

SKU:
CAB24488
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$155 - $431
Frequently bought together:

Description

CD105 Polyclonal Antibody (CAB24488)

The CD105 Polyclonal Antibody offered by Assay Genie is a valuable tool for researchers studying CD105, a cell surface marker involved in angiogenesis and stem cell differentiation. Raised in rabbits, this antibody is highly specific and reacts well with human samples, making it ideal for various research applications such as Western blotting.CD105, also known as endoglin, is a crucial regulator of blood vessel formation and is overexpressed in tumor blood vessels, making it a potential therapeutic target for cancer treatment. By binding to the CD105 protein, this antibody allows for the detection and analysis of CD105 expression in different cell types, providing valuable insights for studies in vascular biology and cancer research.

Understanding the role of CD105 in angiogenesis and stem cell function is essential for developing targeted therapies for diseases such as cancer and cardiovascular disorders. The CD105 Polyclonal Antibody from Assay Genie is a reliable tool for researchers seeking to investigate the function of CD105 in various physiological and pathological processes.

Product Name:CD105 Polyclonal Antibody
Product Code:CAB24488
Reactivity:Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:Mouse lung

Enables protein homodimerization activity and transforming growth factor beta binding activity. Involved in several processes, including circulatory system development; positive regulation of cell differentiation; and regulation of gene expression. Acts upstream of or within circulatory system development and positive regulation of angiogenesis. Located in endothelial microparticle. Is expressed in several structures, including brain; cardiovascular system; extraembryonic vascular system; and lung. Used to study arteriovenous malformations of the brain and hereditary hemorrhagic telangiectasia. Human ortholog(s) of this gene implicated in arteriovenous malformation; arteriovenous malformations of the brain; breast cancer; hereditary hemorrhagic telangiectasia; and intracranial aneurysm. Orthologous to human ENG (endoglin).

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 27-581 of mouse CD105 (NP_031958.2).
Sequence:ERVGC DLQPV DPTRG EVTFT TSQVS EGCVA QAANA VREVH VLFLD FPGML SHLEL TLQAS KQNGT ETQEV FLVLV SNKNV FVKFQ APEIP LHLAY DSSLV IFQGQ PRVNI TVLPS LTSRK QILDW AATKG AITSI AALDD PQSIV LQLGQ DPKAP FLCLP EAHKD MGATL EWQPR AQTPV QSCRL EGVSG HKEAY ILRIL PGSEA GPRTV TVMME LSCTS GDAIL ILHGP PYVSW FIDIN HSMQI LTTGE YSVKI FPGSK VKGVE LPDTP QGLIA EARKL NASIV TSFVE LPLVS NVSLR ASSCG GVFQT TPAPV VTTPP KDTCS PVLLM SLIQP KCGNQ VMTLA LNKKH VQTLQ CTITG LTFWD SSCQA EDTDD HLVLS SAYSS CGMKV TAHVV SNEVI ISFPS GSPPL RKKVQ CIDMD SLSFQ LGLYL SPHFL QASNT IELGQ QAFVQ VSVSP LTSEV TVQLD SCHLD LGPEG DMVEL IQSRT AKGSC VTLLS PSPEG DPRFS FLLRV YMVPT PTAGT LSCNL ALRPS TLSQE VYKTV SMRLN IVSPD LSGKG
Synonyms:Endo, CD105, S-endoglin
Calculated MW:70kDa
Observed MW:Refer to figures

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