The CD103 Polyclonal Antibody (CAB10005) is a valuable tool for research involving the CD103 protein, a marker of regulatory T cells involved in immune tolerance and inflammation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications including Western blot and immunohistochemistry.CD103, also known as integrin alpha E, is a cell surface protein found on regulatory T cells that play a crucial role in maintaining immune tolerance and preventing excessive inflammation.
Research into the function of CD103 is important for gaining insights into immune responses in conditions such as autoimmune diseases, cancer, and inflammatory disorders.Using the CD103 Polyclonal Antibody allows for the detection and analysis of CD103 expression in different cell types and tissues, making it an essential tool for studies in immunology and cancer research. By understanding the role of CD103 in immune regulation, researchers can develop targeted therapies to modulate immune responses in various disease contexts.
Product Name:
CD103 Polyclonal Antibody
SKU:
CAB23053
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant protein of mouse CD103.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
CD103; aM290; alpha-E1; A530055J10; alpha-M290
Positive Sample:
Mouse thymus
Conjugate:
Unconjugated
Calculated MW:
129kDa
Observed MW:
150kDa
Predicted to enable metal ion binding activity. Predicted to act upstream of or within cell adhesion and integrin-mediated signaling pathway. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; lymph node; nasal septum; and nucleus pulposus. Orthologous to human ITGAE (integrin subunit alpha E).
Purification Method:
Affinity purification
Gene ID:
16407
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Mouse thymus, using CD103 Rabbit pAb (CAB23053) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.