The CCZ1 Polyclonal Antibody (PAC051366) is a valuable tool for researchers studying the CCZ1 protein, which plays a crucial role in cellular processes such as autophagy and vesicle trafficking. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds specifically to CCZ1, allowing for accurate detection and analysis in a variety of cell types.CCZ1 is a key player in the regulation of autophagy, a process that removes damaged organelles and proteins from cells, as well as in vesicle trafficking, which is essential for the transport of molecules within cells.
Dysregulation of these processes has been linked to various diseases, including neurodegenerative disorders and cancer. By studying the function of CCZ1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets. Overall, the CCZ1 Polyclonal Antibody is a valuable tool for researchers in the fields of cell biology, molecular biology, and biomedicine who are interested in exploring the role of CCZ1 in health and disease. Its high specificity and reliability make it an essential component of any research project involving the CCZ1 protein.
Antibody Name:
CCZ1 Antibody (PACO51366)
Antibody SKU:
PACO51366
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Human, Rat
Immunogen:
Recombinant Human Vacuolar fusion protein CCZ1 homolog protein (201-482AA)
Western Blot. Positive WB detected in: Rat liver tissue, Rat lung tissue. All lanes: CCZ1 antibody at 2.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 56 kDa. Observed band size: 56 kDa..
Background:
Acts in concert with MON1A, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form.
Synonyms:
Vacuolar fusion protein CCZ1 homolog, CCZ1, C7orf28A
UniProt Protein Function:
CCZ1: Belongs to the CCZ1 family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7p22.1Cellular Component: cytoplasm; intracellular membrane-bound organelle; lysosomal membrane