The CCT7 Polyclonal Antibody (CAB12146) is a valuable tool for researchers studying CCT7, a key protein involved in chaperonin-mediated protein folding. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to CCT7, researchers can accurately detect and analyze this protein in a variety of cell types, making it an essential tool for studies in cell biology and protein folding mechanisms.CCT7, a subunit of the chaperonin-containing TCP-1 (CCT) complex, is essential for maintaining protein homeostasis by assisting in the folding of newly translated proteins.
Dysregulation of CCT7 has been linked to various diseases, including neurodegenerative disorders and cancer, highlighting its importance in cellular function. Investigating the role of CCT7 can provide valuable insights into protein folding pathways and potentially uncover new therapeutic targets for disease intervention.Overall, the CCT7 Polyclonal Antibody is a reliable reagent for researchers seeking to explore the function and regulation of CCT7 in cellular processes. Its high specificity and sensitivity make it a powerful tool for understanding the molecular mechanisms underlying protein folding and its implications in health and disease.
Product Name:
CCT7 Rabbit Polyclonal Antibody
SKU:
CAB12146
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 310-500 of human CCT7 (NP_006420.1).
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.
Purification Method:
Affinity purification
Gene ID:
10574
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CCT7 Rabbit pAb (CAB12146) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
