The CCT6B Polyclonal Antibody (CAB14615) is a vital tool for researchers studying CCT6B, a chaperonin subunit involved in protein folding and cell maintenance. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in various experimental techniques, including Western blotting. By specifically binding to the CCT6B protein, researchers can accurately detect and analyze this important molecule in a variety of cell types, making it an essential component for studies focusing on cellular biology and protein folding mechanisms.
CCT6B, a subunit of the essential chaperonin complex, assists in the folding of newly synthesized proteins, ensuring proper protein function and cellular health. Understanding the role of CCT6B in protein folding processes is crucial for unraveling the mechanisms underlying various diseases, such as neurodegenerative disorders and cancer, where protein misfolding plays a significant role. By dissecting the function of CCT6B, researchers can potentially identify novel therapeutic targets and pathways for intervention in these debilitating conditions.
Product Name:
CCT6B Rabbit Polyclonal Antibody
SKU:
CAB14615
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-340 of human CCT6B (NP_006575.2).
This gene encodes a molecular chaperone that is a member of the chaperonin-containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10693
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CCT6B Rabbit pAb (CAB14615) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
