CCT5 Rabbit Polyclonal Antibody (CAB6549)
- SKU:
- CAB6549
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CCT5 Rabbit Polyclonal Antibody |
SKU: | CAB6549 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CCT5 (NP_036205.1). |
Sequence: | MASM GTLA FDEY GRPF LIIK DQDR KSRL MGLE ALKS HIMA AKAV ANTM RTSL GPNG LDKM MVDK DGDV TVTN DGAT ILSM MDVD HQIA KLMV ELSK SQDD EIGD GTTG VVVL AGAL LEEA EQLL DRGI HPIR IADG YEQA ARVA IEHL DKIS DSVL VDIK DTEP LIQT AKTT LGSK VVNS CHRQ MAEI AVNA VLTV ADME RRDV DFEL IKVE GKVG GRLE DTKL IKGV IVDK DFSH PQMP KKVE DAKI AILT CPFE PPKP KTKH KLDV TS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CCTE; HEL-S-69; PNAS-102; CCT-epsilon; TCP-1-epsilon; CCT5 |
Positive Sample: | HeLa,BT-474,MCF7,U-937,Mouse spleen,Mouse thymus,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13.
Purification Method: | Affinity purification |
Gene ID: | 22948 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |