CCT4 Rabbit Polyclonal Antibody (CAB6548)
- SKU:
- CAB6548
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CCT4 Rabbit Polyclonal Antibody |
SKU: | CAB6548 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-390 of human CCT4 (NP_006421.2). |
Sequence: | PTII SESF QKAL EKGI EILT DMSR PVEL SDRE TLLN SATT SLNS KVVS QYSS LLSP MSVN AVMK VIDP ATAT SVDL RDIK IVKK LGGT IDDC ELVE GLVL TQKV SNSG ITRV EKAK IGLI QFCL SAPK TDMD NQIV VSDY AQMD RVLR EERA YILN LVKQ IKKT GCNV LLIQ KSIL RDAL SDLA LHFL NKMK IMVI KDIE REDI EFIC KTIG TKPV AHID QFTA DMLG SAEL AEEV NLNG SGKL LKIT GCAS PGKT VTIV V |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:100 - 1:500 |
Synonyms: | SRB; Cctd; CCT-DELTA; CCT4 |
Positive Sample: | MCF7,THP-1,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Melanosome, centrosome, cilium basal body, cytoskeleton, microtubule organizing center. |
Calculated MW: | 58kDa |
Observed MW: | 60kDa |
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).
Purification Method: | Affinity purification |
Gene ID: | 10575 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |