CCR7 Rabbit Monoclonal Antibody (CAB0121)
- SKU:
- CAB0121
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | CCR7 Rabbit Monoclonal Antibody |
SKU: | CAB0121 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CCR7 (P32248). |
Sequence: | MDLG KPMK SVLV VALL VIFQ VCLC QDEV TDDY IGDN TTVD YTLF ESLC SKKD VRNF KAWF LPIM YSII CFVG LLGN GLVV LTYI YFKR LKTM TDTY LLNL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7; CCR7 |
Positive Sample: | A-549,Jurkat,C6,Mouse lung,Mouse spleen,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
The protein encoded by this gene is a member of the G protein-coupled receptor family.This receptor was identified as a gene induced by the Epstein-Barr virus (EBV),and is thought to be a mediator of EBV effects on B lymphocytes.This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes.It has been shown to control the migration of memory T cells to inflamed tissues,as well as stimulate dendritic cell maturation.The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.Signals mediated by this receptor regulate T cell homeostasis in lymph nodes,and may also function in the activation and polarization of T cells,and in chronic inflammation pathogenesis.Alternative splicing of this gene results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1236 |
Clone Number: | ARC0231 |
Storage Buffer: | Store at -20℃.Avoid freeze/thaw cycles.Buffer:PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |