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CCR6 Monoclonal Antibody [P4C6AT] (CPAB0009)

SKU:
CPAB0009
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
P4C6AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

CCR6 Monoclonal Antibody [P4C6AT] (CPAB0009)

The CCR6 Polyclonal Antibody (CPAB0009) is a valuable tool for researchers studying the CCR6 protein, a chemokine receptor involved in the migration and activation of immune cells. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications.CCR6 is known to be expressed on various immune cell types, including T cells and dendritic cells, and plays a critical role in regulating immune responses. Its involvement in inflammatory processes and the recruitment of immune cells to sites of infection or inflammation make it an important target for research in immunology and autoimmune diseases.

By using the CCR6 Polyclonal Antibody, researchers can effectively detect and analyze the expression of CCR6 in different cell types and tissues, providing insights into its function and potential as a therapeutic target. This antibody is a valuable tool for studies aiming to elucidate the role of CCR6 in various immune-related diseases, including inflammatory conditions, autoimmune disorders, and cancer.

Product Name:CCR6 Antibody
Product Sku:CPAB0009
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CCR6 mAb , is derived from hybridization of mouse Fmyeloma cells with spleen cells from BALB/c mice immunized with recombinant human CCR6 amino acids 1-46 purified from Ecoli.
Clone:P4C6AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:CCR6 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:CCR6 belongs to the beta chemokine receptor family, which is predicted to be a 7 transmembrane protein similar to G protein-coupled receptors. CCR6 is preferentially expressed by immature dendritic cells and memory T cells. The ligand of CCR6 receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). CCR6 receptor has been shown to be vital for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses.
Synonyms:C-C chemokine receptor type 6, LARC receptor, GPR-CY4, Chemokine receptor-like 3, DRY6, G-protein coupled receptor 29, CD196, C-C CKR-6, CC-CKR-6, CCR-6, GPRCY4, CKR-L3, CCR6, CKRL3, CMKBR6, GPR29, STRL22, BN-1, CKR6, DCR2, DRY-6, GPRCY4, GPR-CY4.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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