The CCR4 Polyclonal Antibody (CAB17324) is a vital tool for researchers studying CCR4, a chemokine receptor involved in immune cell migration and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CCR4 protein, this antibody enables the detection and analysis of CCR4 expression in a variety of cell types, making it an essential asset for studies in immunology and inflammatory diseases.CCR4 is known for its role in directing immune cells to sites of inflammation and infection, as well as its involvement in the regulation of allergic responses.
Understanding the function of CCR4 is crucial for uncovering its potential as a therapeutic target in conditions such as cancer, autoimmune disorders, and inflammatory diseases. Through research using the CCR4 Polyclonal Antibody, scientists can gain valuable insights into the mechanisms underlying immune cell migration and explore new treatment strategies for immune-related disorders.
Product Name:
CCR4 Rabbit Polyclonal Antibody
SKU:
CAB17324
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CCR4 (NP_005499.1).
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
Purification Method:
Affinity purification
Gene ID:
1233
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CCR4 Rabbit pAb (CAB17324) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
