CCR2/CKR2 Rabbit Monoclonal Antibody (CAB2385)
- SKU:
- CAB2385
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CCR2
- CC-CKR-2
- CCR-2
- CCR2A
- CCR2B
- CD192
- CKR2
- CKR2A
- CKR2B
- CMKBR2
- MCP-1-R
- C-C chemokine receptor type 2
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | CCR2/CKR2 Rabbit Monoclonal Antibody |
SKU: | CAB2385 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CCR2/CKR2 (P41597). |
Sequence: | MLST SRSR FIRN TNES GEEV TTFF DYDY GAPC HKFD VKQI GAQL LPPL YSLV FIFG FVGN MLVV LILI NCKK LKCL TDIY LLNL AISD LLFL ITLP LWAH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2; CCR2/CKR2 |
Positive Sample: | A-549,U-937,Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.
Purification Method: | Affinity purification |
Gene ID: | 729230 |
Clone Number: | ARC2585 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |