CCR2 Rabbit Polyclonal Antibody (CAB2855)
- SKU:
- CAB2855
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | CCR2 Rabbit Polyclonal Antibody |
SKU: | CAB2855 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human CCR2 (NP_001116513.2). |
Sequence: | KART VTFG VVTS VITW LVAV FASV PGII FTKC QKED SVYV CGPY FPRG WNNF HTIM RNIL GLVL PLLI MVIC YSGI LKTL LRCR NEKK RHRA VRVI FTIM I |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2; CCR2 |
Positive Sample: | RAW264.7 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.
Purification Method: | Affinity purification |
Gene ID: | 729230 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |