The Anti CCR2/CKR2 Antibody (CAB2385) is a highly specific and sensitive tool for researchers studying chemokine receptors and their role in inflammatory responses. This polyclonal antibody is raised in rabbits and has been rigorously validated for use in Western blot applications, making it a reliable choice for detecting CCR2/CKR2 protein in human samples.CCR2/CKR2 is a chemokine receptor involved in the recruitment of monocytes and macrophages to sites of inflammation, making it a key player in the immune response. By targeting this receptor, researchers can gain valuable insights into the mechanisms underlying inflammatory diseases, such as cancer, autoimmune disorders, and chronic inflammatory conditions.
With its high reactivity and specificity, the Anti CCR2/CKR2 Antibody (CAB2385) enables precise detection and analysis of CCR2/CKR2 expression in various cell types, providing researchers with the tools they need to advance their understanding of immune regulation and inflammatory processes. Whether studying immunology, cancer research, or other related fields, this antibody is an invaluable resource for unlocking the mysteries of chemokine receptor signaling pathways.
Product Name:
CCR2/CKR2 Rabbit Monoclonal Antibody
SKU:
CAB2385
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CCR2/CKR2 (P41597).
The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.
Purification Method:
Affinity purification
Gene ID:
729230
Clone Number:
ARC2585
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CCR2/CKR2 Rabbit mAb (CAB2385) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
