The CCNL2 Polyclonal Antibody (CAB14938) is a valuable tool for researchers studying CCNL2, a key protein involved in cell cycle regulation and cancer development. This antibody, produced in rabbits, specifically targets CCNL2 in human samples and is validated for use in various applications, including Western blot analysis. By binding to CCNL2, this antibody allows for precise detection and analysis in different cell types, making it ideal for investigations in cancer biology and cell proliferation studies.CCNL2, also known as cyclin L2, plays a crucial role in regulating cell division and proliferation by interacting with cyclin-dependent kinases.
Dysregulation of CCNL2 has been linked to the development of various cancers, making it a promising target for therapeutic interventions. Research on CCNL2 is essential for understanding the underlying mechanisms of tumorigenesis and identifying potential targets for cancer therapy.By using the CCNL2 Polyclonal Antibody (CAB14938), researchers can gain valuable insights into the function and regulation of CCNL2 in cancer and other diseases, paving the way for the development of novel treatment strategies and diagnostic tools.
Product Name:
Cyclin L2 Rabbit Polyclonal Antibody
SKU:
CAB14938
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-150 of human Cyclin L2 (NP_001307082.1).
The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
81669
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cyclin L2 Rabbit pAb (CAB14938) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
