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Cyclin L2 Rabbit Polyclonal Antibody (CAB14938)

SKU:
CAB14938
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Cyclin L2 Rabbit Polyclonal Antibody
SKU:CAB14938
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 60-150 of human Cyclin L2 (NP_001307082.1).
Sequence:QLYA RKKV DLTH LEGE VEKR KHAI EEAK AQAR GLLP GGTQ VLDG TSGF SPAP KLVE SPKE GKGS KPSP LSVK NTKR RLEG AKKA KADS PVN
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:CCNM; CCNS; PCEE; SB138; ANIA-6B; HLA-ISO; HCLA-ISO; Cyclin L2
Positive Sample:U-251MG,HeLa,Jurkat,A375,LO2
Conjugate:Unconjugated
Cellular Localization:Nucleus speckle.
Calculated MW:58kDa
Observed MW:58kDa

The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification Method:Affinity purification
Gene ID:81669
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Cyclin L2 Rabbit pAb (CAB14938) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.

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