CCNH Monoclonal Antibody [PAT3G6AT] (CPAB0202)
- SKU:
- CPAB0202
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT3G6AT
- Applications:
- WB
- ELISA
Description
CCNH Monoclonal Antibody [PAT3G6AT] (CPAB0202)
The CCNH Polyclonal Antibody (CPAB0202) is a valuable tool for researchers studying the CCNH protein, a key component of the cyclin H complex involved in cell cycle regulation. This rabbit-raised antibody is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CCNH protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential tool for studies in molecular biology and cancer research.The CCNH protein plays a crucial role in regulating cell cycle progression and gene transcription, making it a promising target for research into cancer and other proliferative diseases.
Understanding the function and regulation of CCNH is essential for developing targeted therapies that can interfere with abnormal cell growth and division, leading to potential advances in cancer treatment and personalized medicine. Overall, the CCNH Polyclonal Antibody (CPAB0202) offers researchers a reliable resource for investigating the role of CCNH in cellular processes and disease pathways, contributing to advancements in the field of molecular biology and potential therapeutic interventions.
Product Name: | CCNH Antibody |
Product Sku: | CPAB0202 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human CCNH mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CCNH amino acids 1-323 purified from Ecoli. |
Clone: | PAT3G6AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | CCNH antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2b |
Background: | CCNH is part of the cyclin family that is known for its protein abundance through the cell cycle. Cyclins act as regulators of CDK kinases. CCNH forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, therefore it functions as a CDK-activating kinase (CAK). CCNH and its kinase collaborator are components of TFIIH, as well as RNA polymerase II protein complexes. |
Synonyms: | CCNH, CAK, p34, p37, Cyclin-H, MO15-associated protein. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |