The CCNG1 Polyclonal Antibody (CAB14713) is a valuable tool for researchers studying the CCNG1 gene, which plays a key role in cell cycle regulation. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CCNG1 protein, this antibody allows for the detection and analysis of CCNG1 expression in a variety of cell types, making it a versatile option for studies in cell biology and cancer research.
CCNG1 is a cyclin protein that interacts with cyclin-dependent kinases to control cell cycle progression and growth. Dysregulation of CCNG1 has been implicated in various cancers, making it an important target for understanding tumorigenesis and developing targeted therapies. By studying the role of CCNG1 in cell cycle control, researchers can gain insights into the mechanisms underlying cancer development and potentially identify new therapeutic strategies.
Product Name:
Cyclin G1 Rabbit Polyclonal Antibody
SKU:
CAB14713
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human Cyclin G1 (NP_004051.1).
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
900
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse skeletal muscle, using Cyclin G1 antibody (CAB14713) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
