The CCNB2 Polyclonal Antibody (CAB3351) is a valuable tool for researchers studying the CCNB2 protein, which is involved in cell cycle regulation and DNA replication. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By targeting the CCNB2 protein, researchers can effectively study its expression and function in various cell types, providing insights into processes such as cell division and proliferation.CCNB2, also known as cyclin B2, plays a crucial role in controlling the progression of the cell cycle, making it a key target for research in cancer biology and developmental biology.
Dysregulation of CCNB2 has been linked to tumorigenesis and other diseases, highlighting the importance of understanding its role in cellular processes. The CCNB2 Polyclonal Antibody offers researchers a reliable tool for investigating the function of CCNB2 and its potential implications in various pathological conditions.
Product Name:
Cyclin B2 Rabbit Polyclonal Antibody
SKU:
CAB3351
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Cyclin B2 (NP_004692.1).
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
Purification Method:
Affinity purification
Gene ID:
9133
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Cyclin B2 antibody (CAB3351) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
