The CCNB2 Polyclonal Antibody (CAB16463) is a valuable tool for researchers studying the cell cycle regulator CCNB2. This antibody, produced in rabbits, shows strong reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CCNB2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and cancer research.CCNB2, also known as Cyclin B2, is a key player in cell cycle progression and is implicated in cell division and proliferation.
Dysregulation of CCNB2 has been linked to various cancers and other diseases, making it a promising target for therapeutic interventions. Investigating the role of CCNB2 using this antibody may provide insights into the mechanisms underlying cell cycle control and offer potential strategies for targeting CCNB2 in cancer treatment and other related research areas.
Product Name:
Cyclin B2 Rabbit Polyclonal Antibody
SKU:
CAB16463
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Cyclin B2 (NP_004692.1).
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
Purification Method:
Affinity purification
Gene ID:
9133
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cyclin B2 Rabbit pAb (CAB16463) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
